Probiotics effective against methicillin resistant staphylococcus aureus (MRSA)

Methicillin-resistant staphylococcus aureus (MRSA) is a multidrug resistant microorganism and the principal nosocomial (hospital) pathogen worldwide. MRSA colonisation generally precedes MRSA infection and it plays a major role in the spread of this organism within human communities and healthcare facilities. A biofilm-forming pathogen, it adheres to numerous surfaces, and in humans and animals it main habitats are the nasal membranes and the skin. Such colonies cause life threatening infections such as pneumonia, sepsis, osteomyelitis and infectious endocarditis. Patients with MRSA colonisation are often colonised for long periods of time. This being so, approximately 50 percent of MRSA patients are still colonised after one year (Karska-Wysocki, Bazo & Smoragiewicz, 2010).

It is suggested that MRSA colonies may be present in an individuals global microbial population as part of the natural balance of his/her own microbial flora (Karska-Wysocki, Bazo & Smoragiewicz, 2010). As a result of becoming part of this essential ecological system, any threat to the normal balance of the entire flora has to be taken into account when attempting to eradicate MRSA. In a recent study, researchers from the University of Quebec, Montreal, evaluated the in vitro antimicrobial activity of lactobacillus acidophilus and lactobacillus casei, against pathogenic MSRA from human clinical isolates (Karska-Wysocki, Bazo & Smoragiewicz, 2010). The results of this study showed that lactobacillus acidophilus and lactobacillus casei produce antimicrobial components that can inhibit the growth and eliminate MRSA cells. The most effective solution contained 64 percent lactobacillus acidophilus and 34 percent lactobacillus casei.

Karska-Wysocki, B., Bazo, M. & Smoragiewicz, W. 2010. Antibacterial activity of lactobacillus acidophilus and lactobacillus casei against methicillin resistant staphylococcus aureus. Microbiological Research, 165, 674-686.

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