There is evidence to suggest that children diagnosed with eosinophilic gastrointestinal disease and food intolerance may be at risk of Coenzyme Q10 deficiency. This has been shown to lead to gastrointestinal dysmotility, pain, allergies, neuromuscular pain, headaches and seizures. In a recent study, researchers from the University of Cinncinnati College of Medicine, evaluated 23 children with recurrent food intolerance and allergies for Coenzyme Q 10 deficiency and mitochondrial abnormalities (Miles, Putnam, Miles, Tang, DeGrauw, Wong, Horn, Foote & Rothenberg, 2011). In this study, muscle biopsies were tested for coenzyme Q 10 levels. It was concluded that children with eosinophilic gastrointestinal disease have significantly decreased muscle coenzyme Q 10, hence, children with recurrent food intolerance and allergies may acquire coenzyme Q 10 deficiency with disease progression.
Miles, M.V., Putnam, P.E., Miles, L., Tang, P.H., DeGrauw, A.J., Wong, B.L., Horn, P.S., Foote, H.L. & Rothenberg, M. E. 2011. Acquired coenzyme Q 10 deficiency in children with recurrent food intolerance and allergies. Mitochondrion, 11, 127-135.